The key naturally occurring lignan precursors to the target metabolite enterolactone commonly found in foods are the lignans ~matairesinol and ~secoisolariciresinol. Of the common food sources of lignans unrefined flaxseed contains the highest amounts at approximately 350 mg/100 g. The target daily intake of lignans from food in order to raise enterolactone levels is approximately 50 mg - 100 mg, roughly speaking this is 3–4 tablespoons or 20 - 30 grams of unrefined flaxseed per day. Due to the over processing of food and a low intake of fruits, vegetables and unrefined grains most people do not get enough lignans in their daily diet. Average intake in the US diet is less than 1mg per day; well below the levels that research indicates to achieve health benefits. As an alternate source of lignans, HMRlignan™ is a highly efficient precursor of enterolactone (see bioavailability & pharmacokinetics). HMRlignan™ is standardized to contain 80,000 mg/100g of lignans and the daily dosage to raise enterolactone levels is 10 - 30mg daily meaning it can be easily dosed in one-a-day capsules or tablets or included into new or existing multi-ingredient formulations.

Lignans in Food