HMRlignan™ is a naturally occurring plant lignan, 7-hydroxymatairesinol, from the Norway spruce (picea abies). In humans 7-hydroxymatairesinol is a direct metabolic precursor of the mammalian lignan, enterolactone. Clinical research has shown HMRlignan™ to be a highly efficient enterolactone precursor. In a multiple dose 4 week-study with healthy volunteers, HMRlignan™ was well tolerated with no adverse effects. In addition to raising enterolactone levels HMRlignan™ also provides significant blood plasma levels of the strong antioxidant and free radical scavenger 7-hydroxymatairesinol1.

As a direct enterolactone precursor, HMRlignan™ offers the health benefits of other lignan sources - such as flax lignans - in a low cost, low dosage and highly bioavailable form.